1-Pyrrolidinecarboxylic acid, 2-(bromomethyl)-, 1,1-dimethylethyl ester, (2R)-
(R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate
CAS: 1039826-29-3
Molecular Formula: C10H18BrNO2
1-Pyrrolidinecarboxylic acid, 2-(bromomethyl)-, 1,1-dimethylethyl ester, (2R)- - Names and Identifiers
1-Pyrrolidinecarboxylic acid, 2-(bromomethyl)-, 1,1-dimethylethyl ester, (2R)- - Physico-chemical Properties
| Molecular Formula | C10H18BrNO2 |
| Molar Mass | 264.16 |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| Sensitive | Irritant |
| MDL | MFCD12912139 |
1-Pyrrolidinecarboxylic acid, 2-(bromomethyl)-, 1,1-dimethylethyl ester, (2R)- - Risk and Safety
| Hazard Class | IRRITANT |
1-Pyrrolidinecarboxylic acid, 2-(bromomethyl)-, 1,1-dimethylethyl ester, (2R)- - Introduction
The (R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate is an organic compound having the formula C12H21BrNO2.
Nature:
(R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate is a colorless to pale yellow liquid with a special odor. It has a density of 1.21 g/cm ^ 3 and a boiling point of 165-166°C. This compound is soluble in common organic solvents such as ethanol, acetone and dichloromethane.
Use:
(R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate are often used as important intermediates in organic synthesis reactions. It can be used to synthesize a variety of organic compounds, such as drugs and pesticides.
Preparation Method:
(R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate can be synthesized by the following steps:
1. In the presence of methyl bromide, pyrrolidine is reacted with tert-butyl hypocarbonate to obtain tert-butyl (2R)-2-(bromomethyl) pyrrolidine-l-carbinolate.
2. The product is reacted with silver carbonate to obtain (R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate.
Safety Information:
For (R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate safety information, general laboratory safety procedures need to be followed. It may cause irritation to the eyes, skin, and respiratory system, so wear appropriate protective equipment such as goggles, lab gloves, and protective masks during operation. In addition, should be stored in a cool, dry place, away from the fire source and open flame.
Nature:
(R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate is a colorless to pale yellow liquid with a special odor. It has a density of 1.21 g/cm ^ 3 and a boiling point of 165-166°C. This compound is soluble in common organic solvents such as ethanol, acetone and dichloromethane.
Use:
(R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate are often used as important intermediates in organic synthesis reactions. It can be used to synthesize a variety of organic compounds, such as drugs and pesticides.
Preparation Method:
(R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate can be synthesized by the following steps:
1. In the presence of methyl bromide, pyrrolidine is reacted with tert-butyl hypocarbonate to obtain tert-butyl (2R)-2-(bromomethyl) pyrrolidine-l-carbinolate.
2. The product is reacted with silver carbonate to obtain (R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate.
Safety Information:
For (R)-tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate safety information, general laboratory safety procedures need to be followed. It may cause irritation to the eyes, skin, and respiratory system, so wear appropriate protective equipment such as goggles, lab gloves, and protective masks during operation. In addition, should be stored in a cool, dry place, away from the fire source and open flame.
Last Update：2024-04-09 20:52:54
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